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[DOI] [PubMed] [Google Scholar] 125.Lu S.C., Ge J.L

In this enzymatic reaction, GSH becomes oxidized to GSSG, which is recycled back to GSH by the NADPH-dependent GSSG reductase as shown in Figure 2

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When to Consider Changing Approaches If a therapy has been implemented consistently and with high fidelity for a reasonable period typically three to six months without evidence of meaningful progress, it is appropriate to reconsider the approach